Applications: Supporting Cancer Research with the Lumascope

Cutaneous T‐cell lymphoma (CTCL) Imaging with the Lumascope

A recent peer-reviewed study led by researchers from McGill University and Harvard explored molecular factors involved in cutaneous T-cell lymphoma (CTCL), a rare form of skin cancer. Among the many tools used in the study, the Etaluma Lumascope played a key role in the researchers’ ability to visualize and quantify cellular activity through immunofluorescence imaging.

The team used the Lumascope to perform imaging of CTCL cell lines stained for Ki67, a marker commonly used to evaluate cell proliferation. By acquiring high-quality fluorescence images, the researchers were able to assess differences in proliferation between control and experimental groups where gene expression was altered. This helped them evaluate the potential impact of a gene called GTSF1 on cancer progression.

Though the study utilized the previous-generation Lumascope 720, today’s Lumascope 820 offers even greater imaging performance for live-cell and fixed-cell fluorescence applications. 

Why Researchers Choose Lumascope

Etaluma’s Lumascope series continues to support academic and clinical researchers who need dependable, space-efficient imaging systems. In this CTCL study, the Lumascope allowed the team to:

• Capture detailed fluorescence images of cultured cells using minimal bench space
• Perform image-based quantification of proliferation using common nuclear markers
• Work within incubator conditions to maintain live or fixed samples

With intuitive software and no need for bulky components, the Lumascope line provides flexibility without compromising image quality. Its LED-based illumination and widefield optics make it a reliable option for users seeking consistent results across multi-day or high-throughput workflows.

The full article, including imaging data collected with the Lumascope, is available here.